In a large oven-safe skillet, heat the olive oil over medium-high heat. Season the chicken breasts with garlic powder, onion powder, cumin, salt, and pepper.
Add the seasoned chicken to the skillet and sear for about 4-5 minutes on each side, until golden brown.
In a mixing bowl, combine the salsa verde and softened cream cheese, stirring until well blended.
Pour the creamy salsa verde mixture over the seared chicken in the skillet, ensuring the chicken is well-coated.
Sprinkle shredded cheddar cheese evenly over the chicken.
Transfer the skillet to the preheated oven and bake for 25-30 minutes, or until the chicken is cooked through and the cheese is bubbly.
Remove from the oven and let it rest for a few minutes before serving.
Garnish with chopped cilantro and serve with lime wedges on the side.